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  • The FDA announced the approval of the new weight reduction drug on Sept. 11, 2014. The drug name is Contrave. Using two separate drugs to lose weight can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with fat loss and the individuals who go through it one should err along the side of caution and allow FDA do its job and demand some investigation be done so that the public understands the side effects and perils associated with the medications before we take them. Keep in mind that drug companies will be in business to earn money and that they would say almost anything to keep people on their own medications. Researchers found out that participants investing in this drug for a year, dropped a few pounds within a month and have kept the body weight off through the entire 56 weeks of the study. Contrave is a combination from the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which might be made up of more than one active ingredient, that might make them more potent and safer. Combo-pilling could be the newest fad or also the newest to come under scrutiny and thus it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular may be the fact that since right now there are no long term prescription weightloss pills that have been authorized by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures are a side effect with Contrave and must not be taken in those with seizure disorders. The drug may also raise hypertension and pulse rate, and must not be used in those with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not used in patients with uncontrolled high blood pressure levels, as well as by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients for the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation. "This will be the first drug I'm alert to that targets both appetite and reward centres inside brain," he was quoted saying.